Hevylite is a quick, simple and highly sensitive laboratory serum test for measuring intact immunoglobulin monoclonal proteins. It identifies and measures IgGκ, IgGλ, IgAκ, IgAλ, IgMκ and IgMλ individually. These proteins are assessed in pairs, e.g. IgGκ/IgGλ, to produce ratios.
Traditional blood tests for monoclonal gammopathies are serum protein electrophoresis (SPE or SPEP) with scanning densitometry, CZE (capillary zone electrophoresis) and/or immunofixation electrophoresis (IFE) together with serum free light chain immunoassays.
Hevylite can benefit your lab because it:
provides greater sensitivity than electrophoretic methods
overcomes technical challenges observed with electrophoresis such as co-migration, non-linearity and dye saturation
maximizes workflow through automation and reduces “hands-on” time
provides quantitative results and avoids subjective interpretation of gels
reduces the number of different tests needed to get a result, especially for IgA monoclonal proteins
